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Mounjaro vs Wegovy:
Complete Comparison 2025

Choosing between Mounjaro and Wegovy for weight loss in Manchester? Both prescription
treatments are available at TheChemist Live in Whitefield, Manchester, with expert pharmacist
consultations and same-day service.

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Serving Manchester, Salford, Bury, Prestwich, Trafford, Stockport, and Oldham with both in-clinic and virtual consultations

Quick Comparison

Key differences between both medications

Average Weight Loss

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Which is More Effective? Clinical Evidence

Direct comparison of clinical trial results and real-world effectiveness data

Mounjaro Clinical Results (SURMOUNT-1 Trial)

2,539 participants in landmark clinical trial

22.5%

Average weight loss at
highest dose (15mg)

91%

Lost at least 5%
body weight

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

20.7%

Average weight loss
at 2.4mg dose

856%

Lost at least 5%
body weight

Direct Comparison & Manchester Patient Insights

1.8-2%

Greater weight loss with Mounjaro in head-to-
head studies

Earlier

Wegovy approved earlier with longer real-
world safety data

Both

Highly effective when combined with
lifestyle changes

Dosing Schedule & Administration

Understanding the Manchester treatment protocols and administration guidelines

Mounjaro Dosing (Manchester Protocol)

22.5%

Average weight loss at
highest dose (15mg)

91%

Lost at least 5%
body weight

Month

Dose

Purpose

Month 1

2.5mg weekly

Initiation, tolerance assessment

Month 2

5mg weekly

Therapeutic dose begins

Month 3

7.5mg weekly

Increased effectiveness

Month 4

10mg weekly

Higher therapeutic dose

Month 5

12.5mg weekly

Maximum dose approach

Month 6+

15mg weekly

Maximum maintenance dose

Wegovy Dosing (Manchester Protocol)

22.5%

Average weight loss at
highest dose (15mg)

91%

Lost at least 5%
body weight

Month

Dose

Purpose

Month 1

0.25mg weekly

Initiation phase

Month 2

0.5mg weekly

Early titration

Month 3

1mg weekly

Mid-range dose

Month 4

1.7mg weekly

Therapeutic range

Month +

2.4mg weekly

Maximum maintenance dose

Dosing Schedule & Administration

Understanding the Manchester treatment protocols and administration guidelines

Administration for Both Medications

Frequently Asked Questions

Wegovy Dosing (Manchester Protocol)

Who Should Choose Which Treatment?

Personalized guidance based on your individual health profile and goals

Who Should Choose Mounjaro?

Mounjaro may be better if:

You want maximum weight loss potential

Clinical data shows higher average weight loss, dual hormone action provides additional benefit

You have type 2 diabetes

Superior blood sugar control, may allow reduction in other diabetes medications

You experienced significant nausea with Wegovy

Generally better gastrointestinal tolerability, lower discontinuation rates

You prefer newer technology

Latest advancement in weight loss medication with most recent clinical data

Patient Profile Example:

Male, age 42, BMI 38, type 2 diabetes, previous Wegovy user experiencing nausea, seeking maximum weight loss - Mounjaro may be preferable.

Who Should Choose Wegovy?

Wegovy may be better if:

You prefer established track record

Longer time on market since 2021, more extensive real-world safety data

You're concerned about newer medications

Well-established safety profile, used by millions worldwide

Your insurance covers Wegovy

Some insurance policies cover Wegovy specifically - check with your provider

You have cardiovascular disease

More extensive cardiovascular outcome data, SELECT trial showed benefits

Patient Profile Example:

Female, age 55, BMI 34, history of heart disease, cautious about new medications, prioritizing safety data - Wegovy may be preferable.

Availability in Manchester

Both treatments available at TheChemist Live Whitefield with comprehensive support

TheChemist Live Whitefield

Location & Coverage

📍 210 Bury New Rd, Whitefield, Manchester M45 6GG

Serving Areas:

Opening Hours

Mon-Fri: 09:00-17:00

Sat-Sun: Closed

Virtual Consultations

7 days/week

By appointment

Consultation Options

In-Clinic Consultations

£20

Virtual Consultations

£20

Delivery Options

Same-day delivery

Next-day delivery

Free delivery

Discreet packaging

Whitefield, Prestwich, Bury areas

All Greater Manchester postcodes

Orders over £XXX

Privacy guaranteed

Contact Information

Side Effects Comparison

Both medications have similar gastrointestinal side effects that typically improve within 4-8 weeks

Location & Coverage

Most common side effects are gastrointestinal and typically improve within 4-8 weeks

Side Effect

Mounjaro

Wegovy

Nausea

25-30% of patients

30-44% of patients

Diarrhea

20-25%

20-30%

Constipation

15-20%

20-24%

Vomiting

10-15%

15-24%

Abdominal Pain

10-12%

10-20%

Fatigue

8-12%

8-11%

Decreased Appetite

Most patients (desired effect)

Most patients (desired effect)

Key Differences

Managing Side Effects at TheChemist Live

Contact Support

Quick Comparison

Get answers to the most common questions about Mounjaro vs Wegovy in Manchester
Which is more effective, Mounjaro or Wegovy?

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Mounjaro (tirzepatide)

Up to 22.5% weight loss, dual GLP-1/GIP action

Wegovy (semaglutide)

Up to 20.7% weight loss, GLP-1 action

Still have questions?

Our Manchester pharmacy team is here to provide personalized guidance and answer any specific
questions about your treatment options.

Ready to Start Your Weight Loss Journey?

Choose between Mounjaro and Wegovy with expert guidance from TheChemist Live Manchester.

Consultation: £20

In-clinic or virtual

Same-day appointments

Expert assessment

Transparent pricing

No hidden fees

Related Pages

Mounjaro Manchester – Full Mounjaro information

Wegovy Manchester – Full Wegovy information

Weight Loss Services – All treatments

Mounjaro Manchester – Full Mounjaro information

Other Service Areas

Weight Loss Salford

Weight Loss Trafford

Weight Loss Stockport

Weight Loss Oldham